
A Short Psychedelic Trip, Weeks of Relief? What the New 5-MeO-DMT Trial Really Shows
A JAMA trial found that one supervised dose of 5-MeO-DMT nasal spray improved depression ratings for some participants. The two-hour headline needs context.
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A JAMA trial found that one supervised dose of 5-MeO-DMT nasal spray improved depression ratings for some participants. The two-hour headline needs context.

COMP360 Phase 3 results, FDA psychedelic guidance and new therapist-training infrastructure all point to the same shift: psychedelic medicine is moving from proving…

COMPASS Pathways now has two positive pivotal Phase 3 trials of COMP360 psilocybin for treatment-resistant depression. Here is what the results actually mean—and…

Mushrooms are having a strange second career: not as food, medicine or psychedelics, but as one of contemporary art’s favorite ways to think…

Entheogens are powerful psychoactive substances used for mystical, spiritual, and therapeutic purposes. This guide explores their use, effects, and legality.

Updated September 2026. This article is educational and is not medical or legal advice.The subject is stranger than the headline and usually less…

Updated September 2026. This article is educational and is not medical or legal advice.Here is the useful version, without the incense-cloud certainty: Some…

Updated September 2026. This article is educational and is not medical or legal advice.Virtual reality can manipulate environment, attention and exposure with extraordinary…

The subject is stranger than the headline and usually less magical than the marketing. Integration is the unfashionable part of psychedelic culture where…

Updated September 2026. This article is educational and is not medical or legal advice.Psychedelic culture has a talent for turning an interesting observation…

Updated September 2026. This article is educational and is not medical or legal advice.Psychedelic research has unusual ethical pressure points: altered suggestibility, intense…

Updated September 2026. This article is educational and is not medical or legal advice.The subject is stranger than the headline and usually less…
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