A Short Psychedelic Trip, Weeks of Relief? What the New 5-MeO-DMT Trial Really Shows
A JAMA trial found that one supervised dose of 5-MeO-DMT nasal spray improved depression ratings for some participants. The two-hour headline needs context.
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Psilocybin Therapy for Depression: Where the Evidence Stands in 20262 min readPsychedelic Medicine Has Entered the Boring Part. That’s Probably Good News.6 min readA Short Psychedelic Trip, Weeks of Relief? What the New 5-MeO-DMT Trial Really Shows7 min read
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A Short Psychedelic Trip, Weeks of Relief? What the New 5-MeO-DMT Trial Really Shows7 min readPsychedelic Medicine Has Entered the Boring Part. That’s Probably Good News.6 min readPsilocybin Has Reached Phase 3. Here’s What COMPASS’s Results Actually Mean6 min read
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A Short Psychedelic Trip, Weeks of Relief? What the New 5-MeO-DMT Trial Really Shows7 min readWhat Are Entheogens? The Word, the Drugs and the Cultural Baggage2 min readIbogaine and Opioid Addiction: Why the Hope Comes With Serious Risk2 min read
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37 published articles matching your selection.
Psychedelic Medicine Has Entered the Boring Part. That’s Probably Good News.
COMP360 Phase 3 results, FDA psychedelic guidance and new therapist-training infrastructure all point to the same shift: psychedelic medicine is moving from proving…
Psilocybin Has Reached Phase 3. Here’s What COMPASS’s Results Actually Mean
COMPASS Pathways now has two positive pivotal Phase 3 trials of COMP360 psilocybin for treatment-resistant depression. Here is what the results actually mean—and…
When Fungi Become Art: Why Mushrooms Keep Escaping the Lab and Invading Galleries
Mushrooms are having a strange second career: not as food, medicine or psychedelics, but as one of contemporary art’s favorite ways to think…
What Are Entheogens? The Word, the Drugs and the Cultural Baggage
Entheogens are powerful psychoactive substances used for mystical, spiritual, and therapeutic purposes. This guide explores their use, effects, and legality.
Ibogaine and Opioid Addiction: Why the Hope Comes With Serious Risk
Updated September 2026. This article is educational and is not medical or legal advice.The subject is stranger than the headline and usually less…
Psychedelics in End-of-Life and Palliative Care: Meaning When Time Is Short
Updated September 2026. This article is educational and is not medical or legal advice.Here is the useful version, without the incense-cloud certainty: Some…
Psychedelics and Virtual Reality: Therapy Tool or Expensive Screensaver?
Updated September 2026. This article is educational and is not medical or legal advice.Virtual reality can manipulate environment, attention and exposure with extraordinary…
Psychedelic Integration: What It Is and Why the Aftermath Matters
The subject is stranger than the headline and usually less magical than the marketing. Integration is the unfashionable part of psychedelic culture where…
Psychedelics and OCD: What the Research Can—and Cannot—Tell Us
Updated September 2026. This article is educational and is not medical or legal advice.Psychedelic culture has a talent for turning an interesting observation…
The Ethics of Psychedelic Research: Consent, Hype, Power and Who Gets Left Out
Updated September 2026. This article is educational and is not medical or legal advice.Psychedelic research has unusual ethical pressure points: altered suggestibility, intense…
Psychedelics and Chronic Pain: Why the Mind-Body Split Was Always Suspicious
Updated September 2026. This article is educational and is not medical or legal advice.The subject is stranger than the headline and usually less…
Start a Reading Journey
Curated connections, not just chronological posts.
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Understanding Consciousness
Begin with altered states, then examine selfhood, neuroscience and mystical experience.
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The Science of Psilocybin
Mechanism, brain imaging, clinical evidence and the importance of replication.
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Psychedelic Art Through History
A tour from visual traditions and symbolism to modern curation and the museum.
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Exploring DMT
Chemistry, reports of entities and the boundaries between experience and interpretation.
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Psychedelics: Evidence and Hype
How to separate intriguing results, missing evidence and overstated headlines.
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The Handoff Myth
Four field notes in their original editorial order.
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